Revisamos las características clínico patológicas en 20 pacientes venezolanos con linfomas de Hodgkin primarios extra-ganglionares, 12 eran del género femenino y 8 del masculino, con edades entre 14 y 72 años (mediana de 29). Cinco se localizaron en los pulmones, 3 en la medula ósea, 3 en las amígdalas palatinas, 3 para-espinales, 2 en el hígado, y uno cada uno en órbita, tejidos blandos, hueso y nariz. Histológicamente, 12 fueron nodulares esclerosantes, 3 celularidad mixta y 5 no clasificables. Analizamos los hallazgos inmunofenotípicos que permiten su identificación y diferenciación con enfermedades que los simulan.
We reviewed the clinic and pathological characteristics in 20 Venezuelan patients with primary extra nodal Hodgkin’s lymphomas, 12 were females and 8 were males, with ages between 14 years and 72 years old (median of 29 years). Five were located in the lungs, 3 in bone marrow, and 3 in tonsils, 3 para-spinal, 2 in liver, and one each in the orbit, soft tissues, bone and nose. Histologically, 12 were nodular sclerosing, 3 mixed cellularity and 5 unclassifiable. We analyzed the immunophenotypical findings that allow its identification and differentiations with diseases which simulate them.